Role of interferons in the treatment of severe acute respiratory syndrome
Identifieur interne : 004671 ( Main/Exploration ); précédent : 004670; suivant : 004672Role of interferons in the treatment of severe acute respiratory syndrome
Auteurs : Jindrich Cinatl Jr [Allemagne] ; Martin Michaelis [Allemagne] ; Martin Scholz [Allemagne] ; Hans Wilhelm Doerr [Allemagne]Source :
- Expert Opinion on Biological Therapy [ 1471-2598 ] ; 2005.
Descripteurs français
- KwdFr :
- Animaux, Antiviraux (usage thérapeutique), Coronavirus (métabolisme), Humains, Interféron alpha (métabolisme), Interféron bêta (métabolisme), Interférons (physiologie), Modèles biologiques, Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (métabolisme), Virus du SRAS (métabolisme).
- MESH :
- métabolisme : Coronavirus, Interféron alpha, Interféron bêta, Syndrome respiratoire aigu sévère, Virus du SRAS.
- physiologie : Interférons.
- usage thérapeutique : Antiviraux.
- Animaux, Humains, Modèles biologiques, Syndrome respiratoire aigu sévère.
English descriptors
- KwdEn :
- Animals, Antiviral Agents (therapeutic use), Coronavirus (metabolism), Humans, Interferon-alpha (metabolism), Interferon-beta (metabolism), Interferons (physiology), Models, Biological, SARS Virus (metabolism), Severe Acute Respiratory Syndrome (metabolism), Severe Acute Respiratory Syndrome (therapy).
- MESH :
- chemical , metabolism : Interferon-alpha, Interferon-beta.
- chemical , physiology : Interferons.
- chemical , therapeutic use : Antiviral Agents.
- metabolism : Coronavirus, SARS Virus, Severe Acute Respiratory Syndrome.
- therapy : Severe Acute Respiratory Syndrome.
- Animals, Humans, Models, Biological.
Abstract
Severe acute respiratory syndrome (SARS) is caused by the SARS coronavirus (SCV). The disease appeared in the Guandong province of southern China in 2002. The epidemic affected > 8422 patients and caused 908 deaths in 29 countries on 5 continents. Several treatment modalities were tried with limited success to treat SARS and a variety of experimental drugs are under development. Type I interferons (IFNs-α/β) were suggested as potential candidates to treat SARS. Several animal and human coronaviruses, including SCV, were shown to be sensitive to IFNs both in vitro and in vivo. A pilot clinical report showed effectiveness of IFN-α for the treatment of SARS patients. This review summarises antiviral activities of IFNs with special regard to SARS, and reviews the published clinical and experimental data describing the use of IFNs for SARS.
Url:
DOI: 10.1517/14712598.4.6.827
PubMed: 15174965
PubMed Central: 7103669
Affiliations:
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Le document en format XML
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Cinatl@em.uni-frankfurt.de</nlm:aff><country wicri:rule="url">Allemagne</country><wicri:regionArea>Klinikum der Johann Wolfgang Goethe-Universitat, Institut fur Medizinische Virologie, Paul Ehrlich-Str. 40, 60596 Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author></analytic><series><title level="j">Expert Opinion on Biological Therapy</title><idno type="ISSN">1471-2598</idno><idno type="eISSN">1744-7682</idno><imprint><date when="2005">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antiviral Agents (therapeutic use)</term><term>Coronavirus (metabolism)</term><term>Humans</term><term>Interferon-alpha (metabolism)</term><term>Interferon-beta (metabolism)</term><term>Interferons (physiology)</term><term>Models, Biological</term><term>SARS Virus (metabolism)</term><term>Severe Acute Respiratory Syndrome (metabolism)</term><term>Severe Acute Respiratory Syndrome (therapy)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Antiviraux (usage thérapeutique)</term><term>Coronavirus (métabolisme)</term><term>Humains</term><term>Interféron alpha (métabolisme)</term><term>Interféron bêta (métabolisme)</term><term>Interférons (physiologie)</term><term>Modèles biologiques</term><term>Syndrome respiratoire aigu sévère ()</term><term>Syndrome respiratoire aigu sévère (métabolisme)</term><term>Virus du SRAS (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Interferon-alpha</term><term>Interferon-beta</term></keywords><keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Interferons</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Coronavirus</term><term>SARS Virus</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Coronavirus</term><term>Interféron alpha</term><term>Interféron bêta</term><term>Syndrome respiratoire aigu sévère</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Interférons</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Humans</term><term>Models, Biological</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Humains</term><term>Modèles biologiques</term><term>Syndrome respiratoire aigu sévère</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Severe acute respiratory syndrome (SARS) is caused by the SARS coronavirus (SCV). The disease appeared in the Guandong province of southern China in 2002. The epidemic affected > 8422 patients and caused 908 deaths in 29 countries on 5 continents. Several treatment modalities were tried with limited success to treat SARS and a variety of experimental drugs are under development. Type I interferons (IFNs-α/β) were suggested as potential candidates to treat SARS. Several animal and human coronaviruses, including SCV, were shown to be sensitive to IFNs both in vitro and in vivo. A pilot clinical report showed effectiveness of IFN-α for the treatment of SARS patients. This review summarises antiviral activities of IFNs with special regard to SARS, and reviews the published clinical and experimental data describing the use of IFNs for SARS.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Stadler, K" uniqKey="Stadler K">K STADLER</name></author><author><name sortKey="Masignani, V" uniqKey="Masignani V">V MASIGNANI</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M EICKMANN</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS PEIRIS</name></author><author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY YUEN</name></author><author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD OSTERHAUS</name></author><author><name sortKey="Stohr, K" uniqKey="Stohr K">K STOHR</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vastag, B" uniqKey="Vastag B">B VASTAG</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davidson, A" uniqKey="Davidson A">A DAVIDSON</name></author><author><name sortKey="Siddell, S" uniqKey="Siddell S">S SIDDELL</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, N" uniqKey="Lee N">N LEE</name></author><author><name sortKey="Hui, D" uniqKey="Hui D">D HUI</name></author><author><name sortKey="Wu, A" uniqKey="Wu A">A WU</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Loutfy, Mr" uniqKey="Loutfy M">MR LOUTFY</name></author><author><name sortKey="Blatt, Lm" uniqKey="Blatt L">LM BLATT</name></author><author><name sortKey="Siminowitch, Ka" uniqKey="Siminowitch K">KA SIMINOWITCH</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Poutanen, Sm" uniqKey="Poutanen S">SM POUTANEN</name></author><author><name sortKey="Low, De" uniqKey="Low D">DE 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ABRAHAM</name></author><author><name sortKey="Stojdl, Df" uniqKey="Stojdl D">DF STOJDL</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Balachandran, S" uniqKey="Balachandran S">S BALACHANDRAN</name></author><author><name sortKey="Roberts, Pc" uniqKey="Roberts P">PC ROBERTS</name></author><author><name sortKey="Brown, Le" uniqKey="Brown L">LE BROWN</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Staehli, P" uniqKey="Staehli P">P STAEHLI</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Janzen, C" uniqKey="Janzen C">C JANZEN</name></author><author><name sortKey="Kochs, G" uniqKey="Kochs G">G KOCHS</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Anderson, Sl" uniqKey="Anderson S">SL ANDERSON</name></author><author><name sortKey="Carton, Jm" uniqKey="Carton J">JM CARTON</name></author><author><name sortKey="Lou, J" uniqKey="Lou J">J LOU</name></author><author><name sortKey="Xing, L" uniqKey="Xing L">L XING</name></author><author><name sortKey="Rubin, By" uniqKey="Rubin B">BY RUBIN</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Patterson, Jb" uniqKey="Patterson J">JB PATTERSON</name></author><author><name sortKey="Thomis, Dc" uniqKey="Thomis D">DC THOMIS</name></author><author><name sortKey="Hans, Sl" uniqKey="Hans S">SL HANS</name></author><author><name sortKey="Samuel, Ce" uniqKey="Samuel C">CE SAMUEL</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saunders, Lr" uniqKey="Saunders L">LR SAUNDERS</name></author><author><name sortKey="Barber, Gn" uniqKey="Barber G">GN BARBER</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y LIU</name></author><author><name sortKey="Emerson, Rb" uniqKey="Emerson R">RB EMERSON</name></author><author><name sortKey="Samuel, Ce" uniqKey="Samuel C">CE SAMUEL</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jayan, Gc" uniqKey="Jayan G">GC JAYAN</name></author><author><name sortKey="Casey, Jl" uniqKey="Casey J">JL CASEY</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sperber, Sj" uniqKey="Sperber S">SJ SPERBER</name></author><author><name sortKey="Hayden, Fg" uniqKey="Hayden F">FG HAYDEN</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pei, J" uniqKey="Pei J">J PEI</name></author><author><name sortKey="Sekellick, Mj" uniqKey="Sekellick M">MJ SEKELLICK</name></author><author><name sortKey="Marcus, Pi" uniqKey="Marcus P">PI MARCUS</name></author><author><name sortKey="Choi, Is" uniqKey="Choi I">IS CHOI</name></author><author><name sortKey="Collison, Ew" uniqKey="Collison E">EW COLLISON</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Minagawa, H" 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sortKey="Laude, H" uniqKey="Laude H">H LAUDE</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Collins, Ar" uniqKey="Collins A">AR COLLINS</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pitkaranta, A" uniqKey="Pitkaranta A">A PITKARANTA</name></author><author><name sortKey="Nokso Koivisto, J" uniqKey="Nokso Koivisto J">J NOKSO-KOIVISTO</name></author><author><name sortKey="Jantti, V" uniqKey="Jantti V">V JANTTI</name></author><author><name sortKey="Takala, A" uniqKey="Takala A">A TAKALA</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Turner, Rb" uniqKey="Turner R">RB TURNER</name></author><author><name sortKey="Felton, A" uniqKey="Felton A">A FELTON</name></author><author><name sortKey="Kosak, K" uniqKey="Kosak K">K KOSAK</name></author><author><name sortKey="Kelsey, Dk" uniqKey="Kelsey D">DK KELSEY</name></author><author><name sortKey="Mescievitz, Ck" uniqKey="Mescievitz C">CK MESCIEVITZ</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tyrrell, Da" uniqKey="Tyrrell D">DA TYRRELL</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Melian, Eb" uniqKey="Melian E">EB MELIAN</name></author><author><name sortKey="Plosker, Gl" uniqKey="Plosker G">GL PLOSKER</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Enserink, M" uniqKey="Enserink M">M ENSERINK</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Harle, P" uniqKey="Harle P">P HARLE</name></author><author><name sortKey="Lauret, E" uniqKey="Lauret E">E LAURET</name></author><author><name sortKey="Pitha, Pm" uniqKey="Pitha P">PM PITHA</name></author><author><name sortKey="De Maeyer, E" uniqKey="De Maeyer E">E DE MAEYER</name></author><author><name sortKey="Carr, Dj" uniqKey="Carr D">DJ CARR</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Antonetti, F" uniqKey="Antonetti F">F ANTONETTI</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Antonelli, G" uniqKey="Antonelli G">G ANTONELLI</name></author><author><name sortKey="Scagnolari, C" uniqKey="Scagnolari C">C SCAGNOLARI</name></author><author><name sortKey="Vincenzi, E" uniqKey="Vincenzi E">E VINCENZI</name></author><author><name sortKey="Clementi, H" uniqKey="Clementi H">H CLEMENTI</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stroher, U" uniqKey="Stroher U">U STROHER</name></author><author><name sortKey="Dicaro, A" uniqKey="Dicaro A">A DICARO</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Manns, Mp" uniqKey="Manns M">MP MANNS</name></author><author><name sortKey="Cornberg, M" uniqKey="Cornberg M">M CORNBERG</name></author><author><name sortKey="Wedemeyer, H" uniqKey="Wedemeyer H">H WEDEMEYER</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baker, De" uniqKey="Baker D">DE BAKER</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pepinsky, Rb" uniqKey="Pepinsky R">RB PEPINSKY</name></author><author><name sortKey="Lepage, Dj" uniqKey="Lepage D">DJ LEPAGE</name></author><author><name sortKey="Chakraborty, A" uniqKey="Chakraborty A">A CHAKRABORTY</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lang, Zw" uniqKey="Lang Z">ZW LANG</name></author><author><name sortKey="Zhang, Lj" uniqKey="Zhang L">LJ ZHANG</name></author><author><name sortKey="Zhang, Sj" uniqKey="Zhang S">SJ ZHANG</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Groot, As" uniqKey="De Groot A">AS DE GROOT</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ho, Jc" uniqKey="Ho J">JC HO</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Glass, Wg" uniqKey="Glass W">WG GLASS</name></author><author><name sortKey="Rosenberg, Hf" uniqKey="Rosenberg H">HF ROSENBERG</name></author><author><name sortKey="Murphy, Pm" uniqKey="Murphy P">PM MURPHY</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gniadek, P" uniqKey="Gniadek P">P GNIADEK</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>District de Darmstadt</li><li>Hesse (Land)</li></region><settlement><li>Francfort-sur-le-Main</li></settlement></list><tree><country name="Allemagne"><region name="Hesse (Land)"><name sortKey="Cinatl Jr, Jindrich" sort="Cinatl Jr, Jindrich" uniqKey="Cinatl Jr J" first="Jindrich" last="Cinatl Jr">Jindrich Cinatl Jr</name></region><name sortKey="Doerr, Hans Wilhelm" sort="Doerr, Hans Wilhelm" uniqKey="Doerr H" first="Hans Wilhelm" last="Doerr">Hans Wilhelm Doerr</name><name sortKey="Michaelis, Martin" sort="Michaelis, Martin" uniqKey="Michaelis M" first="Martin" last="Michaelis">Martin Michaelis</name><name sortKey="Scholz, Martin" sort="Scholz, Martin" uniqKey="Scholz M" first="Martin" last="Scholz">Martin Scholz</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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